Intervertebral Disc-on-a-Chip as Advanced In Vitro Model for Mechanobiology Research and Drug Testing: A Review and Perspective
Discogenic back pain is one of the most diffused musculoskeletal pathologies and a hurdle to a good quality of life timbren gmfk25s for millions of people.Existing therapeutic options are exclusively directed at reducing symptoms, not at targeting the underlying, still poorly understood, degenerative processes.Common intervertebral disc (IVD) disea